てんかんと安静時fMRIの研究一覧

ちょっと頼まれたついでにここにチラ裏。

傾向としては2000年代中盤まではEEGとの同時測定がスタンダードのようですが，近年は解析手法の発展によりfMRI単独施行の研究が増えている模様。以下に機能的結合とEEG同時測定に大別してまとめてある。


機能的結合もしくはそれに類するもの ************************************

Ann Neurol. 2006 Feb;59(2):335-43.
Functional connectivity networks are disrupted in left temporal lobe epilepsy.
Waites AB, Briellmann RS, Saling MM, Abbott DF, Jackson GD.
http://www.ncbi.nlm.nih.gov/pubmed/16404743

Hum Brain Mapp. 2007 Oct;28(10):1023-32.
Temporal lobe interictal epileptic discharges affect cerebral activity in "default mode" brain regions.
Laufs H, Hamandi K, Salek-Haddadi A, Kleinschmidt AK, Duncan JS, Lemieux L.
http://www.ncbi.nlm.nih.gov/pubmed/17133385

J Magn Reson Imaging. 2008 Jun;27(6):1214-20.
Differential interictal activity of the precuneus/posterior cingulate cortex revealed by resting state functional MRI at 3T in generalized vs. partial seizure.
Lui S, Ouyang L, Chen Q, Huang X, Tang H, Chen H, Zhou D, Kemp GJ, Gong Q.
http://www.ncbi.nlm.nih.gov/pubmed/18504738

Hum Brain Mapp. 2009 May;30(5):1580-91.
Decreased basal fMRI functional connectivity in epileptogenic networks and contralateral compensatory mechanisms.
Bettus G, Guedj E, Joyeux F, Confort-Gouny S, Soulier E, Laguitton V, Cozzone PJ, Chauvel P, Ranjeva JP, Bartolomei F, Guye M.
http://www.ncbi.nlm.nih.gov/pubmed/18661506

Neurosci Lett. 2009 Jul 24;458(3):97-101. Epub 2009 Apr 23.
Impaired attention network in temporal lobe epilepsy: a resting FMRI study.
Zhang Z, Lu G, Zhong Y, Tan Q, Yang Z, Liao W, Chen Z, Shi J, Liu Y.
http://www.ncbi.nlm.nih.gov/pubmed/19393717

J Neurol. 2009 Oct;256(10):1705-13. Epub 2009 Jun 2.
Impaired perceptual networks in temporal lobe epilepsy revealed by resting fMRI.
Zhang Z, Lu G, Zhong Y, Tan Q, Liao W, Chen Z, Shi J, Liu Y.
http://www.ncbi.nlm.nih.gov/pubmed/19488674

PLoS One. 2010 Jan 8;5(1):e8525.
Altered functional connectivity and small-world in mesial temporal lobe epilepsy.
Liao W, Zhang Z, Pan Z, Mantini D, Ding J, Duan X, Luo C, Lu G, Chen H.
http://www.ncbi.nlm.nih.gov/pubmed/20072616

BMC Neurosci. 2010 Jun 2;11:66.
Asymmetrical hippocampal connectivity in mesial temporal lobe epilepsy: evidence from resting state fMRI.
Pereira FR, Alessio A, Sercheli MS, Pedro T, Bilevicius E, Rondina JM, Ozelo HF, Castellano G, Covolan RJ, Damasceno BP, Cendes F.
http://www.ncbi.nlm.nih.gov/pubmed/20525202



EEGとのコンバインネタ**************************************

Epilepsia. 1999 Jul;40(7):912-20.
Hemodynamic and metabolic aspects of photosensitive epilepsy revealed by functional magnetic resonance imaging and magnetic resonance spectroscopy.
Hill RA, Chiappa KH, Huang-Hellinger F, Jenkins BG.
http://www.ncbi.nlm.nih.gov/pubmed/10403215

Hum Brain Mapp. 2006 Jun;27(6):488-97.
Negative BOLD responses to epileptic spikes.
Kobayashi E, Bagshaw AP, Grova C, Dubeau F, Gotman J.
http://www.ncbi.nlm.nih.gov/pubmed/16180210

Epilepsia. 2006 Feb;47(2):444-8.
Linking generalized spike-and-wave discharges and resting state brain activity by using EEG/fMRI in a patient with absence seizures.
Laufs H, Lengler U, Hamandi K, Kleinschmidt A, Krakow K.
http://www.ncbi.nlm.nih.gov/pubmed/16499775

Neuroimage. 2006 Jul 1;31(3):1015-24. Epub 2006 Mar 20.
Analysis of EEG-fMRI data in focal epilepsy based on automated spike classification and Signal Space Projection.
Liston AD, De Munck JC, Hamandi K, Laufs H, Ossenblok P, Duncan JS, Lemieux L.
http://www.ncbi.nlm.nih.gov/pubmed/16545967

Neuroimage. 2008 Jan 15;39(2):608-18. Epub 2007 Jul 19.
BOLD and perfusion changes during epileptic generalised spike wave activity.
Hamandi K, Laufs H, Nöth U, Carmichael DW, Duncan JS, Lemieux L.
http://www.ncbi.nlm.nih.gov/pubmed/17920297